1. Signaling Pathways
  2. Epigenetics
  3. Histone Acetyltransferase
  4. Histone Acetyltransferase Inhibitors

Histone Acetyltransferase Inhibitors

CBP/p300

GCN5/PCAF

TIP60

MOZ/MORF

HBO1

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

Histone Acetyltransferase Inhibitors & Activators
Product Name CBP/p300 GCN5/PCAF TIP60 MOZ/MORF HBO1 Purity
Curcumin
CBP/p300
        98.84%
A-485
CBP/p300
        99.87%
C646
CBP/p300
        99.78%
WM-3835        
HBO1
99.78%
SGC-CBP30
CBP/p300
        99.83%
PF-9363      
MOZ/MORF
  99.64%
Butyrolactone 3  
GCN5, IC50: 100 μM
      99.31%
NSC 228155
KIX-KID, IC50: 0.36 μM
        ≥98.0%
Anacardic Acid
p300-HAT, IC50: 8.5 μM
PCAF, IC50: 5 μM
      98.86%
CTB
CBP/p300
        99.93%
MG 149
CBP/p300
 
TIP60
    99.86%
WM-1119      
MOZ/MORF
  99.57%
PU139
CREBBP, IC50: 2.49 μM
p300, IC50: 5.35 μM
GCN5, IC50: 8.39 μM
PCAF, IC50: 9.74 μM
      99.14%
NEO2734
CBP/p300
        99.63%
Garcinol  
GCN5/PCAF
      ≥99.0%
CPI-1612
CBP/p300
        99.74%
TH1834    
TIP60
    99.60%
CPTH2  
GCN5
      99.82%
GSK 4027  
GCN5/PCAF
      98.01%
WM-8014      
MOZ/MORF
  99.81%
TTK21
CBP/p300
        99.39%
CTPB
CBP/p300
        ≥99.0%
PF-CBP1 hydrochloride
CREBBP, IC50: 125 nM
EP300, IC50: 363 nM
CBP, Kd: .19 μM
        99.99%
YF-2
CBP, EC50: 2.75 μM
GCN5, EC50: 49.31 μM
GCN5/PCAF, EC50: 29.04 μM
      98.76%
L002
CBP/p300
        99.02%
I-CBP112
CBP/p300
        98.20%
TH1834 dihydrochloride    
TIP60
    99.68%
GNE-207
CBP, IC50: 1 nM
       
GNE-272
CBP/p300
        99.76%
Histone Acetyltransferase Inhibitor II
CBP/p300
        99.01%
CBP/p300-IN-12
CBP/p300, IC50: 166 nM
        99.70%
Procyanidin B3
CBP/p300
        99.63%
PCAF-IN-2  
PCAF, IC50: 5.31 μM
      ≥98.0%
YF-2 hydrochloride
CBP, EC50: 2.75 μM
GCN5, EC50: 49.31 μM
GCN5/PCAF, EC50: 29.04 μM
      99.61%
Lys-CoA TFA
p300, IC50: 50-500 nM
        99.42%
GSK4028  
GCN5/PCAF
      98.06%
TPOP146
CBP/p300
        98.98%
CBP/p300-IN-10
EP300, IC50: 26 nM
CREBBP, IC50: 39 nM
        98.69%
MOZ-IN-2      
MOZ/MORF
  99.87%
NiCur
CBP-HAT, IC50: 0.35 μM
        99.11%
Naphthol AS-E
KIX-KID, IC50: 2.26 μM
        ≥98.0%
Curcumin-d6
CBP/p300
        98.00%
CBP/p300-IN-19 hydrochloride
p300-HAT, IC50: 1.4 μM
CBP-HAT, IC50: 2.2 μM
PCAF, IC50: >100 μM
     
CBP/p300-IN-5
CBP/p300
       
CBP/p300-IN-20
CBP/p300, pIC50: 10.1
        98.03%
NSC 694623  
PCAF, IC50: 15.9 μM
      99.36%
CPTH2 hydrochloride  
GCN5
     
DS17701585
EP300, IC50: 0.04 μM
CBP, IC50: 0.15 μM
       
CBP/p300-IN-18
EP300, IC50: .056 μM
       
Ep300/CREBBP-IN-4
EP300, IC50: 0.024 μM
CREBBP, IC50: 0.064 μM
       
CBP/p300-IN-15
CBP, IC50: 28 nM
p300, IC50: 2.5 nM
       
Ep300/CREBBP-IN-3
EP300, IC50: 0.056 μM
CREBBP, IC50: 0.095 μM
       
P300 bromodomain-IN-1
p300, IC50: 49 nM
       
B026
p300, IC50: 8.1 nM
CBP, IC50: 9.5 nM
       
Ep300/CREBBP-IN-2
EP300, IC50: 0.052 μM
CREBBP, IC50: 0.148 μM
       
CBP/p300-IN-17
EP300, IC50: .18 μM
       
CAY10669  
PCAF, IC50: 662 μM
     
Ep300/CREBBP-IN-8
EP300, IC50: 0.014 μM
CREBBP, IC50: 0.018 μM
       
CBP/p300-IN-19
p300-HAT, IC50: 1.4 μM
CBP-HAT, IC50: 2.2 μM
PCAF, IC50: >100 μM
     
KCN1
p300